Arch Linux, cachyos Proton/GE-proton.
Before I've manually redownloaded client and replaced files in data folder and in main game folder, autoloot worked perfectly with SuperWoW and Interact combination. After, it would only open window and won't loot unless I click with mouse. With trial and error I've figured out it's the issue with .exe files, since replacing anything else does not cause this for me. But launching game again with old .VanillaFixes.exe works perfectly as before.
I'll provide more information if needed, but I don't see a way to fix it on my end currently.